Could protein PSP94 be the key to understanding the etiology of prostate cancer?
“Several lines of evidence support a role for infectious agents in the development of prostate cancer. […] Circumcision before first sexual intercourse is associated with a reduction in the relative risk of [prostate cancer] in this study population. These findings are consistent with research supporting the infectious/inflammation pathway in prostate carcinogenesis.” Wright et al, 2012 (see also the Strickler Goedert Hypothesis and criticism of this study  )
Here are five more studies which directly tie a fungal infection to benign prostatic hyperplasia (BPH). Circumstantial evidence also links chronic prostatitis (CP/CPPS) to a fungal infection.
"PSP94, what is it good for?" explores the hypothesis that a sexually transmissible infectious agent targeted by PSP94 is causing prostate cancer and BPH. It thoroughly reviews PSP94 studies from the scientific literature, and reaches a robust conclusion. It is published under the Creative Commons Attribution-NonCommercial-NoDerivatives License (v4.0 International), allowing free distribution and reproduction. When researchers manage to genetically identify the infectious agent responsible for prostate cancer, preventative strategies will be developed which may save millions of lives. Identification has recently become possible with the advent of unbiased high-throughput sequencing technology which is available in well funded labs ; two novel pathogens have already been identified using this technique, one of which has been linked to another type of cancer  . The following studies were based in part on "PSP94, what is it good for?":
“Following the theory proposed by Laurence, the present study provides initial epidemiological support for the hypothesis that the PSP94 protein may inhibit the adverse effects of a sexually transmitted pathogen on prostatic tissue, since men who carry the T allele of rs10993994 have been shown to have lower PSP94 expression in prostate tissue and lower PSP94 concentrations in urine, and are also at increased risk for [prostate cancer]. […] PSP94 does exhibit strong fungicidal activity, and Laurence proposes the novel idea that a candidate STI organism may be fungal in origin.” Stott-Miller et al, 2013