Could protein PSP94 be the key to understanding the etiology of prostate cancer? Read the following four quotes and decide for yourself.
“Several
lines of evidence support a role for infectious agents in the development of
prostate cancer. […]
Circumcision before first sexual intercourse is associated with a reduction in
the relative risk of [prostate cancer] in this study population. These findings
are consistent with research supporting the infectious/inflammation pathway in
prostate carcinogenesis.” Wright et al, 2012 (see also the Strickler Goedert Hypothesis and criticism of this study [1] [2])
“The most strongly associated SNP, rs10993994, is 2 bp upstream of the transcription start site of [PSP94's gene]. Its location and the strength of the association raises the possibility that this SNP may be causally related to [prostate cancer] risk.” Eeles et al, 2008 “Additional copies of the [rs10993994] risk allele for prostate cancer, T, correlated with lower levels of [PSP94].” Xu et al, 2010
“Seminal
plasma displayed prominent fungicidal effects at a 1000-fold dilution. […] The fungicidal activity of seminal plasma was mediated by [PSP94].” Edstrom et al, 2012
Here are five more quotes which directly tie PSP94 to benign prostatic hyperplasia (BPH).
"PSP94, what is it good for?" explores the hypothesis that a sexually transmissible infectious agent targeted by PSP94 is causing prostate cancer and BPH. It thoroughly reviews PSP94 studies from the scientific literature, and reaches a robust conclusion. It is published under the Creative Commons Attribution-Noncommercial License (US/v3.0), allowing free distribution and reproduction. When researchers manage to genetically identify the infectious agent responsible for prostate cancer, preventative strategies will be developed which will save millions of lives. Identification has recently become possible with the use of next-generation sequencing technology available in well funded labs. |
|
